Biochemistry – Medical School Exams
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BIOCHEMISTRY TOPICS
BLOCK 1:
- Structure of DNA and chromosomes
- DNA replication, recombination and repair
- RNA synthesis and processing in bacteria and eukaryotic cells
- Transcription and RNA metabolism
- The genetic code
- Molecular mechanism of protein synthesis
- Genetic code and translation
- Gene regulation of prokaryotic and eukaryotic cells
- Gene expression
- Recombinant DNA technology
- Genetic engineering in medicine
- Molecular medicine
- Chemical bonds and ionizable groups
- Protein structure
- The amino acids
- Protein structure analysis
- Enzymes
- Catalysis and inhibitors
- Hemoglobin and myoglobin structure
- Myosin-based molecular motors
- Sequence-specific DNA binding proteins and collagen
BLOCK 2:
- Bioenergetics: basic concepts of energy generation
- ATP formation in mitochondria (Oxidative phosphorylation)
- Generation of energy form Acetyl CoA (TCA cycle)
- Fatty acid catabolism
- Generation of energy from carbohydrates
- Fatty acid oxidation
- Glycolysis and CHO metabolism
- Amino acid catabolism
- Regulation of energy metabolism
- Basic concepts in the regulation of storage and mobilization of energy reserves
- Glycogen storage and breakdown
- Fatty acid synthesis and storage
- Tryglyceride metabolism
- Ketone body metabolism
- Protein turnover
- Regulation of metabolism
- Metabolic disorders
BLOCK 3:
- Amino acid biosynthesis
- One-carbon metabolism
- Amino acid-derived products
- Purine and pyrimidine metabolism
- Phospholipids
- Phospholipases, eicosanoic acids, phingolipids
- Metabolism of cholesterol
- Lipid digestion and transport
- Steroid hormones and proteoglycans
- Glycoproteins
- Membrane structure and targeting
- Membrane transport
- Cell signaling mechanisms
- Nutrition: macronutrients, vitamins and minerals
Tags: Cell signaling, DNA replication, eicosanoic acids, genetic code, Glycoproteins, Lipid digestion and transport, Membrane structure and targeting, Membrane transport, Metabolism of cholesterol, Molecular mechanism of protein synthesis, recombination and repair, RNA synthesis and processing in bacteria and eukaryotic cells, sphingolipids, Steroid hormones and proteoglycans, Structure of DNA and chromosomes, Transcription and RNA metabolism, vitamins and minerals




